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Megaloblastic Anemia
Megaloblastic anemia is a
blood disorder characterized by red blood cells that are larger than
normal, low white
blood cell (WBC) count, and low platelet
count resulting from a deficiency
of folate or vitamin
B-12.
A thorough explanation of the mechanism
by which folate stimulates DNA synthesis and red blood cell development to
treat or prevent megaloblastic anemia is given on the University
of Virginia School of Medicine website.
Folic acid consumption may mask vitamin B12
deficiency by correcting the anemia (which is easier to detect), but not
addressing the other symptoms of vitamin B12 deficiency. Persons
at risk for vitamin B12 deficiency should be careful to
obtain the RDA of vitamin B12, in addition to folic acid.
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