Woman, previous NTD-affected pregnancy…
The U.S.
Preventive Services Taskforce recommends that periconceptional intake of
folic acid be 4000 mcg daily for women with a previous affected pregnancy.[71]
This is 10 times the
recommended dose for other women. Treatment should start 1 month before the time they plan
to become pregnant and extend throughout the first 3 months of pregnancy, unless
contraindicated.
Women should be advised not to
attempt to achieve the 4000 mcg daily dosage of folic acid by taking over-the-counter or
prescription multivitamins containing folic acid because of the possibility of ingesting
harmful levels of other vitamins, for example, Vitamin A.
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